BioIncubator - our Pipeline

BioIncubator - our Pipeline

With disruptive Innovations into the Future

The BRAINBioIncubator comprises promising R&D projects with high value creation potential. The developments are carried out in-house or together with industry partners. 

 

Current pipeline projects

Project Description Status

Deucrictibant as
biopharmaceutical
ingredient

The compound Deucrictibant (former name: PHA121) has been identified and characterized at our research site in Potsdam, Germany (AnalytiCon Discovery), and has been licensed to Pharvaris N.V. (Nasdaq: PHVS). The compound for the treatment of bradykinin-mediated diseases as HAE is currently in clinical development. 

BRAIN Biotech AG concludes major pharma compound transaction valued up to EUR 128.88 million from its BioIncubator

Enzyme for wound healing

Aurase® is an enzymatic compound developed by BRAIN Biotech for the cleansing of chronic wounds. SolasCure Ltd., a company founded with the participation of BRAIN Biotech, is working on the registration of this medical compound. Initial clinical development has yielded promising data demonstrating the enzyme's great potential as a clinically effective means of debridement (removal of infected and non-viable tissue) and its safe application. The compound has successfully completed phase 2a clinical trials. SolasCure is currently preparing for phase 2b/3 clinical development and is in the process of financing further business activities.

SolasCure completes phase II clinical trial, demonstrating accelerated healing with Aurase Wound Gel

Gold recovery
from waste streams

Development of microorganisms and a bioprocess for the environmentally friendly recovery of gold.

Upscaling process with industrial partner.

G-dase® E / G-dase® M
enzymes for genome editing

These enzymes are proprietary CRISPR nucleases developed by BRAIN Biotech AG to build a genome editing technology platform. The development of G-dase® E is aimed, among other things, at a new type of cancer therapy. Both nucleases can also be used for gene editing in industrial biotechnology.

BRAIN Biotech AG and Akribion Therapeutics GmbH sign exclusive pharma licensing agreement for G-dase E® CRISPR-Cas technology

BRAIN Biotech has been granted a key patent for its CRISPR-BMC genome-editing technology

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